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What causes high cortisol levels? Pituitary gland issues Issues with the pituitary gland can cause it to under- or over-produce hormones, including adrenocorticotropic hormone. This is the hormone that triggers the adrenal glands to release cortisol. Pituitary conditions that can cause high cortisol levels include: cancerous pituitary tumors.
Do symptoms of Addison's disease come and go? In rare cases, the symptoms of Addison's disease can develop rapidly causing a condition called acute adrenal failure. Fatigue is the most common symptom of Addison's disease. Affected individuals may have a poor appetite and unintentional weight loss and may develop progressive fatigue and muscle weakness.
Why do I have low cortisol levels? Cortisol is a steroid hormone made by your adrenal glands. Your body also pumps out excess cortisol when you're anxious or under intense stress, which can affect your health if the levels stay too high for too long. If your cortisol levels are too high or too low, you may have a condition that needs treatment.
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