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What is Nccah? Abstract. Congenital adrenal hyperplasia (CAH) is a family of autosomal recessive disorders. Nonclassic CAH (NCCAH) is a less severe form of the disorder, in which there is 20–50% of 21-hydroxylase enzyme activity (vs. 0–5% in classic CAH) and no salt wasting.
Is congenital adrenal hyperplasia deadly? Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder affecting one of the enzymes necessary for the adrenal synthesis of cortisol. Untreated, the condition is lethal in severe cases due to salt crisis and hypoglycemia.
What is non Classical Congenital Adrenal Hyperplasia? Non -classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency (NCAH) is a milder and later onset form of a genetic condition known as congenital adrenal hyperplasia. Women with NCAH are generally born with normal female genitalia.
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